Characterization

Understanding the unique characteristics of extracellular vesicles (EVs) is crucial for advancing research in early detection and disease monitoring.

We employ a range of cutting-edge techniques to comprehensively characterize EVs from diverse biological sources, providing valuable insights into their properties and composition. Our characterization service has a typical turnaround time of up to 4 weeks.

Service offerings

Technique Description
Transmission Electron Microscopy (TEM) Visualize ultrastructure, morphology, and size of EVs
Western Blotting (WB) Detect specific proteins in EV samples
Nanoparticle Tracking Analysis (NTA) Measure size distribution and concentration of EVs
Nanoparticle Flow Cytometry (NanoFCM) Analyze EVs by size and surface markers
Enzyme-linked immunosorbent assay (ELISA) Assess protein content and concentration in EV samples

Representative data

Western blot analysis showed EV markers TSG101, CD9, and CD81 in EVs from plasma, urine, and cells, lacking calnexin (left). TEM analysis displayed a consistently distributed size range of purified EVs (right).