Isolation and purification

Isolating extracellular vesicles (EVs) from complex biological samples is of utmost importance to study their functions, molecular composition, and therapeutic potential.

At Jotbody, we specialize in providing high-purity and high-yield purified EVs from multiple sources including cell culture samples and all human proximal fluids, including plasma, urine, cerebrospinal fluid, amniotic fluid, bronchoalveolar lavage fluid, synovial fluid, sperm, saliva, malignant and pleural effusions of ascites and breast milk.

Service offerings and duration

DurationMethodsDeliverables
10 days
  • Ultracentrifugation (UC)
  • Iodixanol density gradient
  • Size-exclusion chromatography (SEC)
  • EVs in storage buffer or lyophilized formats
  • TEM data
  • Final reports

Representative data

TEM images displaying EVs obtained from human red blood cells (left) and HEK293 cells (right) through UC and SEC isolation methods.