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by Jotbody 21 Aug, 2025Latest Research
Could Proper Nanobody Orientation Unlock Peak Performance in Affinity Chromatography?
What if how you attach a nanobody to resin could dramatically boost binding capacity? A study published on Journal of Chromatography demonstrates exactly that—using SpyCatcher/SpyTag chemistry to directionally orient nanobodies and enhance affinity resin performance.
Read details by Jotbody 19 Aug, 2025Latest Research
What if extracellular vesicles in your blood could reveal whether you’re facing tau-based dementia or TDP-43–related neurodegeneration?
A pioneering 2024 study in Nature Medicine suggests this is possible—using extracellular vesicles (EVs), microscopic messengers released by cells, to carry tell-tale disease markers. Researchers found that two EV proteins—tau isoform ratios (3R/4R) and TDP 43—can accurately differentiate disorders like Frontotemporal Dementia (FTD), Amyotrophic Lateral Sclerosis (ALS), and Progressive Supranuclear Palsy (PSP) using just a blood sample!
Read details by Jotbody 12 Aug, 2025Latest Research
Can Extracellular Vesicles Reveal Sepsis Risk in Burn Patients for Early Detection?
Introduction Burn patients face a high risk of sepsis, a life-threatening complication where early detection can save lives. Traditional diagnostic tools often fail to provide rapid, accurate results, especially during the early stages. A new study explores an innovative approach: using plasma-derived extracellular vesicles (EVs) analyzed by label-free Raman spectroscopy as biomarkers for sepsis in...
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